their effects more rapidly in large doses; it is sometimes even quite
altered in kind. A striking example has just been related in the case of
oxalic acid; which, according to the dose, may corrode the stomach, or
act on the heart, or on the spine, or on the brain. In like manner
arsenic in a small dose may cause gastritis of several days’ duration;
while a large dose may prove fatal in two or three hours by affecting
the action of the heart. White hellebore in small doses excites
inflammation in the stomach and bowels, in larger doses giddiness,
convulsions, coma; and in either way it may prove fatal.